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KMID : 0614620180710020098
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Korean Journal of Gastroenterology
2018 Volume.71 No. 2 p.98 ~ p.102
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Pancreatic Neuroendocrine Tumor Presenting as Acute Pancreatitis
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Kim Min-Jeong
Park Jin-Myung
Lee Sung-Joon
Kang Chang-Don
Kang Myung-Ho
Kim Ji-Hyun
Lee Seung-Koo
Cho Seong-Whi
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Abstract
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We report a case of acute pancreatitis secondary to pancreatic neuroendocrine tumor. A 46-year old man presented with upper abdominal pain. The serum amylase and lipase were elevated. Abdominal computed tomography (CT) and magnetic resonance cholangiopancreatography revealed a 1.7 cm sized mass at the pancreas body with a dilatation of the upstream pancreatic duct and mild infiltrations of peripancreatic fat. An endoscopic ultrasound-guided fine needle biopsy was performed for the pancreatic mass, but only necrotic tissue was observed on the pathologic examination. A chest and neck CT scan revealed anterior mediastinal, paratracheal, and cervical lymph node enlargement, which were indicative of metastasis. An ultrasound-guided core needle biopsy was performed for the enlarged neck lymph node, and pathologic examination revealed a metastatic poorly differentiated carcinoma. Immunohistochemical analysis showed positive staining for synaptophysin, chromogranin A, and CD 56, indicative of a neuroendocrine carcinoma.
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KEYWORD
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Neuroendocrine tumor, Pancreatitis, Endoscopic ultrasound-guided fine needle aspiration
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